Neomycin and polymyxin b sulfates and dexamethasone for stye

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MAXITROL EYE DROPS (NEOMYCIN SULFATE/POLYMYXIN B SULFATE/DEXAMETHASONE)

Maxitrol Eye Drops for Treating Eyelid Inflammation and Infection

Is it a stye, bacterial conjunctivitis, or blepharitis? If you are dealing with inflammation, swelling, and redness on the front of your eyelid where the eyelashes are or on the inner part of your eyelid, you need to see your doctor for treatment and to ensure your sight will not be affected permanently. Maxitrol Eye Drops contains two antibiotic medicines and a corticosteroid that can alleviate your symptoms and kill the bacteria that can cause the infection. The most common bacteria that cause conjunctivitis are Staphylococcus aureus, Haemophilus influenzae, Streptococcus pneumoniae, and Pseudomonas aeruginosa.

How the Active Ingredients Work

The first of the antibiotics in Maxitrol Eye Drops is called Neomycin Sulfate; it interferes with the production of protein that the bacteria need to form a stable bacterial cell membrane. Without this protein, the cell membrane will be damaged. The second antibiotic is Polymyxin Sulfate and it deals with gram-negative bacteria that have a unique outer membrane that protects the bacteria. By interacting with the major component of the tough outer bacterial cell membrane. This action will change the permeability of the outer membrane so the bacteria die as they are no longer protected from adverse environmental conditions. Then there is Dexamethasone, the corticosteroid that will suppress the production of inflammatory chemicals and reduce the swelling and inflammation.

More Information about Eye Conditions

Styes are fairly common and everyone has had at least one or two of them over their lifetime. You will see a small, reddened lump on the part of your eyelid where the eyelashes are, or just inside the lid where the oil glands are. Bacteria can enter at the root of your eyelash or into an oil gland and cause the pus-filled lump. Bacterial conjunctivitis is usually caused by the Staphylococcus bacteria and is a common type of pink-eye. Both styes and bacterial conjunctivitis are contagious so precautions need to be taken to avoid passing these on.

Blepharitis is not usually contagious but it can be chronic and hard to treat. Anterior blepharitis is usually caused by Staphylococcus bacteria or from scalp dandruff, while posterior blepharitis is caused by sebum (oil) from acne or dandruff. Identifying the source of your eye condition is important before your doctor prescribes Maxitrol Eye Drops.

Before Instilling Maxitrol Eye Drops

Ask your doctor if Maxitrol Eye Drops are safe to use if you are pregnant, trying to conceive, or are breast feeding. Explain other medical conditions or allergies you have to your doctor and list any OTC, Rx, herbal preparations, and supplements you currently take or use so it can be determined if Maxitrol Eye Drops are the right treatment for your situation.

Proper Use of Maxitrol Eye Drops

Do not drive or attempt any task until your vision returns to normal after using Maxitrol Eye Drops. Do not touch the dropper to any part of your affected eyelid or you could contaminate the rest of the Maxitrol Eye Drops. Keep all medications out of children’s reach and never share with anyone else.

Possible Side Effects of Maxitrol Eye Drops

  • Blurred vision
  • Redness
  • Increased tearing
  • Sensitivity to light

  • Overview
  • Consumer Information
  • Professional Information

Maxitrol Side Effects Center

What Is Maxitrol?

Maxitrol (neomycin and polymyxin B sulfates and dexamethasone) Ophthalmic Suspension Sterile is a combination of two antibiotics and a steroid used to treat bacterial infections of the eyes. Maxitrol is available in generic form.

What Are Side Effects of Maxitrol?

Common side effects of Maxitrol include:

  • stinging/burning of the eyes for 1 to 2 minutes when Maxitrol is applied,
  • irritation,
  • itching,
  • redness,
  • blurred vision,
  • eyelid itching,
  • eyelid swelling, or
  • sensitivity to light.

Serious side effects are generally not expected with Maxitrol. Use of Maxitrol for prolonged or repeated periods may result in a new fungal eye infection and may increase your risk for other eye problems (e.g., glaucoma, cataracts, delayed wound healing). Do not use Maxitrol for longer than prescribed. Tell your doctor if you experience unlikely but serious side effects of Maxitrol including new or worsening eye symptoms (e.g., discharge, swelling, redness), vision problems, or eye pain.

Seek medical care or call 911 at once if you have the following serious side effects:

  • Serious eye symptoms such as sudden vision loss, blurred vision, tunnel vision, eye pain or swelling, or seeing halos around lights;
  • Serious heart symptoms such as fast, irregular, or pounding heartbeats; fluttering in your chest; shortness of breath; and sudden dizziness, lightheartedness, or passing out;
  • Severe headache, confusion, slurred speech, arm or leg weakness, trouble walking, loss of coordination, feeling unsteady, very stiff muscles, high fever, profuse sweating, or tremors.

This document does not contain all possible side effects and others may occur. Check with your physician for additional information about side effects.

Dosage for Maxitrol

Dosing of Maxitrol: One to two drops in the conjunctival sac(s). In severe disease, drops may be used hourly, being tapered to discontinuation as the inflammation subsides. In mild disease, drops may be used up to four to six times daily.

What Drugs, Substances, or Supplements Interact with Maxitrol?

Avoid other eye medications unless approved by your doctor. Before using Maxitrol, tell your doctor if you are taking an oral steroid medication such as prednisone (Deltasone, Orasone, others). Other drugs may also interact with Maxitrol.

Maxitrol During Pregnancy or Breastfeeding

Talk to your doctor before taking any prescription or over-the-counter medicines. During pregnancy, Maxitrol should be used only when prescribed. It is not known if this drug passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Maxitrol (neomycin and polymyxin B sulfates and dexamethasone) Ophthalmic Suspension Sterile Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Neomycin and polymyxin b sulfates and dexamethasone for stye

SLIDESHOW

Pink Eye (Conjunctivitis) Symptoms, Causes, Treatments See Slideshow

Maxitrol Consumer Information

Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

  • blurred vision, tunnel vision, eye pain, or seeing halos around lights;
  • swelling, redness, severe discomfort, crusting or drainage (may be signs of infection);
  • pain behind your eyes, sudden vision changes; or
  • a wound that will not heal.

Common side effects may include:

  • blurred vision; or
  • mild eye irritation.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Read the entire detailed patient monograph for Maxitrol (Neomycin, Polymyxin B and Dexamethasone Ophthalmic)

Neomycin and polymyxin b sulfates and dexamethasone for stye

QUESTION

What causes dry eyes? See Answer

Maxitrol Professional Information

SIDE EFFECTS

Adverse reactions have occurred with corticosteroid/anti-infective combination drugs which can be attributed to the corticosteroid component, the anti-infective component, or the combination. Exact incidence figures are not available since no denominator of treated patients is available.

Reactions occurring most often from the presence of the anti-infective ingredient are allergic sensitizations. The reactions due to the corticosteroid component are: elevation of IOP with possible development of glaucoma, and infrequent optic nerve damage; posterior subcapsular cataract formation; and delayed wound healing. Corticosteroid-containing preparations have also been reported to cause perforation of the globe. Keratitis, conjunctivitis, corneal ulcers, and conjunctival hyperemia have occasionally been reported following use of steroids.

Additional adverse reactions identified from post marketing use include ulcerative keratitis, headache, and Stevens-Johnson syndrome.

The following additional adverse reactions have been reported with dexamethasone use: Cushing's syndrome and adrenal suppression may occur after use of dexamethasone in excess of the listed dosing instructions in predisposed patients, including children and patients treated with CYP3A4 inhibitors.

DRUG INTERACTIONS

No Information provided

Read the entire FDA prescribing information for Maxitrol (Neomycin, Polymyxin B and Dexamethasone Ophthalmic)

© Maxitrol Patient Information is supplied by Cerner Multum, Inc. and Maxitrol Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

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Can I use neomycin and polymyxin B for a stye?

If the condition is identified early, the use of non–neomycin-containing antibiotic ointment such as gentamicin or polymyxin-B and bacitracin ophthalmic ointment combined with frequent applications of warm moist packs usually resolves the problem.

How do you apply neomycin to a stye?

Proper Use Tilt the head back and, pressing your finger gently on the skin just beneath the lower eyelid, pull the lower eyelid away from the eye to make a space. Squeeze a thin strip of ointment into this space.

What is neomycin and polymyxin B sulfates and dexamethasone ophthalmic used for?

NEOMYCIN; POLYMYXIN B; DEXAMETHASONE (nee oh MYE sin; pol i MIX in B; dex a METH a sone) is a combination of a steroid and antibiotics. It helps to reduce swelling, redness, and itching of the eye. It also is used to treat eye infections.

What happens if you put neomycin in your eye?

Stinging/burning of the eyes for 1 to 2 minutes or temporary blurred vision may occur when this medication is applied. If any of these effects last or get worse, tell your doctor or pharmacist promptly.