Polymyxin b tmp eye drops for pink eye

Polytrim Side Effects Center

What Is Polytrim?

Polytrim (polymyxin B sulfate and trimethoprim ophthalmic solution) is an antibiotic indicated in the treatment of surface bacterial infections of the eye, including acute bacterial conjunctivitis, and blepharoconjunctivitis, caused by susceptible strains of the following microorganisms: Staphylococcus aureus, Staphylococcus epidermidis, Streptococcus pneumoniae, Streptococcus viridans, Haemophilus influenzae and Pseudomonas aeruginosa. Polytrim is available in generic form.

What Are Side Effects of Polytrim?

Common side effects of Polytrim include:

• eye irritation (redness, burning, stinging, or itching), and
• hypersensitivity reactions (eyelid swelling, itching, increased redness, tearing, or rash)

Dosage for Polytrim

In mild to moderate infections, instill a dose of one drop of Polytrim in the affected eye(s) every three hours (maximum of 6 doses per day) for a period of 7 to 10 days.

What Drugs, Substances, or Supplements Interact with Polytrim?

Polytrim may interact with other drugs. Tell your doctor all medications and supplements you use.

Polytrim During Pregnancy or Breastfeeding

Tell your doctor if you are pregnant or plan to become pregnant before using Polytrim; it is unknown how it would affect a fetus. It is unknown if Polytrim passes into breast milk. Consult your doctor before breastfeeding.

Additional Information

Our Polytrim (polymyxin B sulfate and trimethoprim ophthalmic solution) Side Effects Drug Center provides a comprehensive view of available drug information on the potential side effects when taking this medication.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

SLIDESHOW

Polytrim Consumer Information

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Get emergency medical help if you have signs of an allergic reaction: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using this medicine and call your doctor at once if you have:

• eye pain, swelling, redness, or severe discomfort;
• crusting or drainage (may be signs of infection);
• swelling or redness of your eyelids; or
• new or worsening symptoms.

Common side effects may include:

• mild burning, stinging, or itching of your eyes.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

QUESTION

Polytrim Professional Information

SIDE EFFECTS

The most frequent adverse reaction to POLYTRIM® Ophthalmic Solution is local irritation consisting of increased redness, burning, stinging, and/or itching. This may occur on instillation, within 48 hours, or at any time with extended use. There are also multiple reports of hypersensitivity reactions consisting of lid edema, itching, increased redness, tearing, and/or circumocular rash. Photosensitivity has been reported in patients taking oral trimethoprim.

Read the entire FDA prescribing information for Polytrim (Polymyxin B Sulfate and Trimethoprim Ophthalmic Solution, USP, Sterile)

© Polytrim Patient Information is supplied by Cerner Multum, Inc. and Polytrim Consumer information is supplied by First Databank, Inc., used under license and subject to their respective copyrights.

• Uses
  • What Is Trimethoprim/Polymyxin B Ophthalmic and How Does It Work?
• Dosages
  • What Are Dosages of Trimethoprim/Polymyxin B Ophthalmic?
• Side Effects
  • What Are Side Effects Associated with Using Trimethoprim/Polymyxin B Ophthalmic?
• Drug Interactions
  • What Other Drugs Interact with Trimethoprim/Polymyxin B Ophthalmic?
• Warnings and Precautions
  • What Are Warnings and Precautions for Trimethoprim/Polymyxin B Ophthalmic?

What Is Trimethoprim/Polymyxin B Ophthalmic and How Does It Work?

Trimethoprim/Polymyxin B Ophthalmic is a prescription medicine used to treat the symptoms of bacterial conjunctivitis and blepharoconjunctivitis.

• Trimethoprim/Polymyxin B Ophthalmic is available under the following different brand names: Polytrim Ophthalmic Solution

What Are Dosages of Trimethoprim/Polymyxin B Ophthalmic?

Adult and pediatric dosage

Ophthalmic solution

• (1mg/10,000 units)/mL

Bacterial Conjunctivitis

Adult dosage

• Instill 1 drop in affected eye(s) every 3 hours for 7-10 days; not to exceed 6 doses/day

Pediatric dosage

• Children below 2 months: Safety and efficacy not established
• Children above 2 years: Instill 1 drop in affected eye(s) every 3 hours for 7-10 days; not to exceed 6 doses/day

Dosage Considerations – Should be Given as Follows: 

• See “Dosages”

What Are Side Effects Associated with Using Trimethoprim/Polymyxin B Ophthalmic?

Common side effects of Trimethoprim/Polymyxin B Ophthalmic include:

• eye irritation (redness, burning, stinging, or itching), 
• eyelid swelling,
• itching,
• increased redness,
• tearing of the eye, and
• rash.

Serious side effects of Trimethoprim/Polymyxin B Ophthalmic include:

• increasing redness, burning, stinging, or itching of the eye.

Rare side effects of Trimethoprim/Polymyxin B Ophthalmic include:

• none 

This is not a complete list of side effects and other serious side effects or health problems that may occur as a result of the use of this drug. Call your doctor for medical advice about serious side effects or adverse reactions. You may report side effects or health problems to FDA at 1-800-FDA-1088.

SLIDESHOW

Pink Eye (Conjunctivitis) Symptoms, Causes, Treatments See Slideshow

What Other Drugs Interact with Trimethoprim/Polymyxin B Ophthalmic?

If your medical doctor is using this medicine to treat your pain, your doctor or pharmacist may already be aware of any possible drug interactions and may be monitoring you for them. Do not start, stop, or change the dosage of any medicine before checking with your doctor, health care provider, or pharmacist first

• Trimethoprim/Polymyxin B Ophthalmic has no noted severe interactions with any other drugs.
• Trimethoprim/Polymyxin B Ophthalmic has no noted serious interactions with any other drugs.
• Trimethoprim/Polymyxin B Ophthalmic has no noted moderate interactions with any other drugs.
• Trimethoprim/Polymyxin B Ophthalmic has no noted minor interactions with any other drugs. 

This information does not contain all possible interactions or adverse effects. Visit the RxList Drug Interaction Checker for any drug interactions. Therefore, before using this product, tell your doctor or pharmacist about all the products you use. Keep a list of all your medications with you and share this information with your doctor and pharmacist. Check with your health care professional or doctor for additional medical advice, or if you have health questions or concerns.

What Are Warnings and Precautions for Trimethoprim/Polymyxin B Ophthalmic?

Contraindications

• Hypersensitivity

Effects of drug abuse

• None

Short-Term Effects

• See “What Are Side Effects Associated with Using Trimethoprim/Polymyxin B Ophthalmic?”

Long-Term Effects

• See “What Are Side Effects Associated with Using Trimethoprim/Polymyxin B Ophthalmic?”

Cautions

• Not for injection into the eye
• Not indicated for prophylaxis or treatment of ophthalmia neonatorum
• Prolonged use may result in the overgrowth of nonsusceptible organisms
• Avoid contaminating the applicator tip with material from the eye, fingers, or another source
• If redness, irritation, swelling, or pain persists or increases, discontinue use immediately and seek medical attention
• Advise patient not to wear contact lenses with active signs and symptoms of ocular bacterial infections or while using antibacterial eyedrops

Pregnancy and Lactation

• Use with caution if the benefits outweigh the risks during pregnancy.
• Lactation
  • Unknown whether distributed in breast milk 

QUESTION

What causes dry eyes? See Answer

From

References

https://reference.medscape.com/drug/polytrim-ophthalmic-solution-trimethoprim-polymyxin-b-ophthalmic-999779#0